Myasthenia Gravis

• Muscle weakness that worsens with activity and improves with rest
• Double vision (diplopia)
• Drooping eyelids (ptosis)
• Difficulty swallowing (dysphagia)
• Shortness of breath
• Muscle weakness in the arms, legs, or neck

Causes

• Autoimmune response: The immune system mistakenly attacks the receptors that transmit nerve signals to muscles.
• Genetic predisposition: Some people may be more susceptible to developing MG due to genetic factors.

Treatment

• Medications:

- Cholinesterase inhibitors (e.g., pyridostigmine) to improve nerve-muscle communication - Immunosuppressants (e.g., prednisone) to reduce immune system activity

• Thymectomy: Surgical removal of the thymus gland, which can help reduce symptoms in some people
• Plasmapheresis: A procedure that removes antibodies from the blood

Management

• Lifestyle modifications: Getting regular rest, avoiding extreme temperatures, and managing stress can help manage symptoms.
• Physical therapy: Gentle exercises and stretches can help maintain muscle strength and flexibility.

Complications

• Myasthenic crisis: A life-threatening exacerbation of muscle weakness that requires immediate medical attention.

If you or someone you know is living with myasthenia gravis, it is essential to work closely with a healthcare team to manage symptoms and prevent complications.